If you are going on vacation, you can use the Listings Status feature to temporarily remove your open listings from Amazon.com until you are ready to process and fulfill orders again. Setting your listings to "Inactive" will prevent customers from placing orders while you're away.
The Listings Status feature can be found on the Seller Account Information page in your seller account. When you set your listings to "Inactive," all of your listings will be removed from the Amazon.com product detail pages and search results within one hour.
When you return from vacation and are ready to sell again, you can set your listings back to "Active." Your listings will begin to appear on the Amazon.com product detail pages and search results within one hour.